The congresswoman defeated Democratic former Gov. Phil Bredesen by closely aligning her bid with President Donald Trump, who drummed up support for her during three visits to the state that he won by 26 percentage points, including a rally in Chattanooga two days before the election.
Blackburn's win represents a rightward shift from the GOP senator she will replace, Bob Corker, who fell in line with Tennessee's historical preference for more-centrist senators and at times was a vocal critic of Trump.
Blackburn worked to undermine Bredesen's popularity and reputation as an independent thinker by tying him to national Democrats at every turn. She rarely diverged from Trump, and touted his proposed U.S.-Mexico border wall and tax cuts while blasting Bredesen's opposition to both. She backed Brett Kavanaugh for Supreme Court the same day Trump nominated him, and criticized Bredesen for taking so long to say he would have supported Kavanaugh's confirmation as well.
First elected to the House in 2002, Blackburn aligned with the tea party movement and regularly appeared on Fox News. She opened her campaign by dubbing herself a "hardcore, card-carrying Tennessee conservative." Before that, she made a name for herself as a state lawmaker who helped lead the revolt against a proposed Tennessee income tax in the early 2000s.
The pricey race set a state record in spending by candidates and outside groups, gaining national interest because of its potential implications for the GOP's slim majority in the Senate.
Pop superstar Taylor Swift even broke her political silence for the Tennessee contest when she went on Instagram to endorse Bredesen and encourage people to vote.
Blackburn took aim at Bredesen for donating to Hillary Clinton and Barack Obama and receiving campaign checks from high-profile Democrats. Although Bredesen largely kept his distance from other well-known Democrats, Blackburn had no qualms bringing Trump and fellow national Republicans to Tennessee.
She welcomed in Vice President Mike Pence twice. The president's son Eric Trump, and U.S. Sens. Marco Rubio of Florida, Lindsey Graham of South Carolina, Joni Ernst of Iowa, Tom Cotton of Arkansas and Thom Tillis of North Carolina also came along for separate campaign events.
Corker, the outgoing senator, had backed Blackburn but refused to campaign against Bredesen, whom he considers a friend. Corker briefly heard out pleas from some peers last winter that he reconsider retirement, prompting a Blackburn spokeswoman to say anyone who thinks she can't win the general election is a "plain sexist pig."
Afterward though, she managed to consolidate support across the GOP's various political circles, including from former U.S. Rep. Stephen Fincher, who briefly opposed her in the primary and called for Corker to run again upon dropping out of the race.